Fossible HIS is a production-grade Hospital Information System on Frappe and ERPNext — EHR, LIS, RIS, pharmacy, billing, insurance, inventory, HR, and accounting on one database and one API. Self-host anywhere with zero per-user fees. Every doctype exposes REST, workflows run in Python, and Hydra MCP gives AI agents a typed, permissioned tool surface from day one.
Platform proof points
The problem
Most hospitals run five to eight disconnected systems. Fossible HIS replaces that sprawl with one integrated CareOps and ERP platform on Frappe.
EMR, billing, inventory, HR, and lab each on separate systems — middleware, training, and license fees multiply.
Encounters do not trigger billing, inventory, or GL automatically — reporting means manual reconciliation.
Proprietary code, cloud-only hosting, and per-seat pricing that scales faster than your patient volume.
Fossible HIS unifies CareOps and ERP on Frappe/ERPNext — one database, one API, self-hosted, agent-ready via Hydra MCP.
Platform
Four operational domains in one Frappe stack — production-ready modules, deeply integrated, customizable through low-code.
FHIR-compliant patient management, encounters, vitals, procedures, medications, nursing tasks, and inpatient ADT — multi-specialty ready.
Full LIS with LOINC, RIS with DICOM, integrated pharmacy with inventory and interaction checks.
Accounting, RCM, procurement, multi-warehouse inventory, HR and payroll — natively wired through ERPNext.
Low-code doctypes, portals, workflow designer, RBAC, audit trails, SSO, and REST on every entity.
Agent-ready
Every doctype is a versioned REST endpoint with filters, pagination, and field selection. Agents read and write through the same surface as your staff — RBAC and audit included.
# An agent fetching active patients
GET /api/resource/Patient
?filters=[["status","=","Active"]]
&fields=["name","first_name","dob"]
&limit_page_length=5
# → JSON response
{ "data": [{ "name": "PAT-0042", ... }] }From registration and ADT through lab, pharmacy, billing, and general ledger — one platform, one truth, no middleware tax.
Appointments, encounters, ADT, bed management, nursing checklists, and discharge — OPD and IPD on one chart.
Lab orders, sample tracking, observations, radiology workflows, and medication requests tied to inventory.
Invoicing, packages, payor contracts, eligibility, claims, and payments — clinical events drive revenue.
GL, procurement, assets, HR, payroll, and multi-site company structure — no separate finance system.
FHIR R4, HL7, DICOM, LOINC, ICD-10, SNOMED-CT — plus HIPAA-ready patterns, ABDM, and NABH support.
Frappe low-code — new doctypes, reports, and workflows in days, not change-order quarters.
Comparison
Most HIMS products stop at clinical workflows. Fossible HIS adds ERP, APIs, and open source — without extra vendors.
| Capability | Traditional HIMS | Fossible HIS + ERPNext |
|---|---|---|
| Clinical workflows (OPD, IPD) | Included | FHIR R4 compliant |
| Lab, radiology, pharmacy | Basic modules | Full LIS, RIS, pharmacy |
| Accounting & GL | Separate system | Multi-currency GL built in |
| Billing & RCM | Basic invoicing | Insurance, claims, packages |
| Inventory & supply chain | Limited or missing | Multi-warehouse ERP |
| HR & payroll | Separate HRIS | Full HRMS on same stack |
| API access | Limited endpoints | REST on every doctype |
| Source & licensing | Proprietary · per-seat | GPL-3.0 · $0 seats |
Ecosystem
You inherit a battle-tested open-source business platform, not a standalone app with a fragile plugin market.
10K+
Run operations on Frappe/ERPNext worldwide.
50K+
Forums, Frappeverse, and implementers.
300+
Extend beyond healthcare when you need to.
$0
GPL-3.0 — full source, no seat tax.
140+
Multi-currency, language, and company.
Low-code
Ship features in days, not months.
Compliance & standards
Agent-ready
REST on every doctype, Python workflows, and Hydra MCP — CareOps and ERP that AI agents can use on day one.
Patient, Appointment, Lab Order, Inventory Item — CRUD via REST out of the box. No separate API layer to build or version.
Server scripts, hooks, and background workers — agents trigger workflows with RBAC, audit trails, and rollback.
Typed MCP tools for any LLM client — read and act on live Fossible HIS through the same permissions as staff.
Every agent action flows through validation, roles, and audit logging — no separate agent backdoor.
Go deeper
Composable stack — Fossible HIS for operations, Medplum for clinical interoperability, and AI services when you need both planes.
Health Central
Espresso Cloud CI/CD, Fossible Sprints dev pods, and healthcare IT services to take Fossible HIS from pilot to production.
Healthcare ITSee Fossible HIS with your use cases — including Hydra MCP across every module. We'll walk through the platform, multi-site needs, and an implementation plan.